Yohimbine has received some attention from the nootropic community for its positive effects on energy, mood and concentration. As a supplement, this alkaloid is derived from the bark of a West African evergreen tree known as Yohimbe. Yohimbine is an active chemical found within Yohimbe bark extract. In many cases, this supplement is used for treating side effects that may be caused by selective serotonin reuptake inhibitors (SSRIs).

On the cognitive enhancement side, Yohimbine is sometimes taken by individuals for its energy-boosting qualities, increased alertness, perpetual awareness, reduced brain fog and even an increase in your motivation levels. It can also have a positive influence on mental performance as it relates to concentration, accuracy in performing tasks, memory, reaction time, and cognitive speed. Medically speaking, this supplement is considered to be a pre-synaptic alpha-2 adrenergic receptor blocking agent or antagonist. What this means is that it tends to increase the activity of the sympathetic nervous system. It is also responsible for increasing the release of adrenaline (epinephrine) and norepinephrine in the bloodstream. This part of the nervous system is involved in controlling and regulating the body’s overall response to stress, as well as triggering the fight or flight response.

In low doses, Yohimbine HCL has been observed to have positive effects on reducing blood pressure. This is thought to be due to an ability to dilate or relax blood vessels. The temporary widening of blood vessels tends to reduce vascular resistance and make blood flow easier. This dilation effect may have a number of sexual benefits as well, leading to increased circulation to sexual organs.

Yohimbine also works by heightening the fat burning process within the human body. This is likely the result of increased thermogenesis which is associated with higher levels of epinephrine and norepinephrine. Yohimbine also inhibits a regulatory process that normally limits your natural fat burning rate. The result is a higher metabolism particularly targeting stored lipids or fat deposits which can improve your diet or weight loss results. This action does seem to be partially negated when the supplement is taken with food.



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